2021-2023

“Total Synthesis of the 2,5-Disubstituted gamma-Pyrone E1 UAE Inhibitor Himeic Acid A.” Lu, H., Handore, K. L.; Wood, T. E.; Shimokura, G. K.; Schimmer, A. D.; Batey, R. A.; Org. Lett. 2023, 25, 7502-7506. (DOI: 10.1021/acs.orglett.3c02761)

“High Accuracy Prediction of PROTAC Complex Structures.” Ignatov, M.; Jindal, A.; Kotelnikov, S.; Beglov, D.; Posternak, G.; Tang, X.; Maisonneuve, P.; Poda, G.; Batey, R. A.; Sicheri, F.; Whitty, A.; Tonge, P. J.; Vajda, S.; Kozakov, D. J. Am. Chem. Soc. 2023, 145, 7123-7135. (DOI: 10.1021/jacs.2c09387)

“N-Alkyl Carbamoylimidazoles as Isocyanate Equivalents: Exploration of Reaction Scope for the Synthesis of Ureas, Hydantoins, Carbamates, Thiocarbamates, and Oxazolidinones.” Bansagi, J.; Wilson-Konderka, C.; Debrauwer, V. Narayanan, P.; Batey, R. A. J. Org. Chem. 2022, 87, 11329-11349. (DOI: 10.1021/acs.joc.2c00803)

“Total Synthesis of Chaiyaphumines A-D: A Comparison of Macrolactonization versus Macrolactamization Approaches.” Lu, H.; Batey, R. A. Tetrahedron Lett. 2022, 108, 154138. (DOI: 10.1016/j.tetlet.2022.154138)

“Discovery and structural characterization of small molecule binders of the human CTLH E3 ligase subunit GID4.” Chana, C.; Maisonneuve, P.; Posternak, G.; Grinberg, N. G. A.; Poirson, J.; Ona, S. M.; Ceccarelli, D. F.; Mader, P.; St-Cyr, D. J.; Pau, V.; Kurinov, I.; Tang, X.; Deng, D.; Cui, W.; Su, W.; Kuai, L.; Soll, R.; Tyers, M.; Röst, H. L.; Batey, R. A.; Taipale, M.; Gingras, A.-C.; Sicheri, F. J. Med. Chem. 2022, 65, 12725-12746. (DOI: 10.1021/acs.jmedchem.2c00509)

“CACHE (Critical Assessment of Computational Hit-finding Experiments): A public–private partnership benchmarking initiative to enable the development of computational methods for hit-finding.” Ackloo, S.; Al-awar, R.; Amaro, R. E.; Arrowsmith, C. H.; Azevedo, H.; Batey, R. A.; Bengio, Y.; Betz, U. A. K.; Bologa, C. G.; Chodera, J. D.; Cornell, W. D.; Dunham, I.; Ecker, G. F.; Edfeldt, K.; Edwards, A. M.; Gilson, M. K.; Gordijo, C. R.; Hessler, G.; Hillisch, A.; Hogner, A.; Irwin, J. J.; Jansen, J. M.; Kuhn, D.; Leach, A. R.; Lee, A. A.; Lessel, U.; Morgan, M. R.; Moult, J.; Muegge, I.; Oprea, T. I.; Perry, B. G.; Riley, P.; Rousseaux, S. A. L.; Saikatendu, K. S.; Santhakumar, V.; Schapira, M.; Scholten, C.; Todd, M. H.; Vedadi, M.; Volkamer, A.; Willson, T. M. Nature Reviews Chemistry 2022. (DOI: 10.1038/s41570-022-00363-z)