2024-Present
“RGFN: Synthesizable Molecular Generation Using GFlowNets.” Koziarski, M.; Rekesh, A. Shevchuk, D.; van der Sloot, A.; Gain ́ski, P.; Bengio, Y.; Liu, C.-H.; Tyers, M.; Batey, R. A. NeurIPS 2024. (https://proceedings.neurips.cc/paper_files/paper/2024/file/53704142f230054140418ecd8857f391-Paper-Conference.pdf)
“Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases” Lin, F.; Mabanglo, M.; Zhou, J. L.; Binepal, G.; Barghash, M.; Wong, K.; Gray-Owen, S.; Batey, R. A.; Houry, W. J. Med. Chem. 2024, 67, 15131–15147. (DOI: 10.1021/acs.jmedchem.4c00773)
“Synthesis of N-Hydroxysuccinimide Esters, N-Acylsaccharins, and Activated Esters from Carboxylic Acids using I2/PPh3.” Handore, K. L.; Lu, H.; Park, H.; Xiong, Q.; Batey, R. A.; J. Org. Chem., 2024, 89, 7598–7608. (DOI: 10.1021/acs.joc.4c00272)
“Targeting Protein Homeostasis with Small Molecules as a Strategy for the Development of Pan-Coronavirus Antiviral Therapies.” Mao, Y.-Q.; Jahanshahi, S.; Malty, R.; Van Ommen, D. A. J.; Wan, Y.; Morey, T. M.; Chuang, S. H. W.; Pavlova, V.; Ahmed, C.; Dahal, S.; Lin, F.; Mangos, M.; Nurtanto, J.; Song, Y.; Been, T.; Christie-Holmes, N.; Gray-Owen, S. D.; Babu, M.; Wong, A. P.; Batey, R. A.; Attisano, L.; Cochrane, A.; Houry. W. A. Commun. Biol. 2024, 7 (1), 1460. (DOI: 10.1038/s42003-024-07143-z)
“The Pan-Canadian Chemical Library: A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening” Schapira, M.; Bedart, C.; Shimokura, G.; West, F. G.; Wood, T. E.; Batey, R. A.; Irwin, J. J.; Schapira, M. Sci. Data 2024, 11, 597. (DOI: 10.1038/s41597-024-03443-5)
“Machine Learning is a Viable Alternative to High Throughput Screening: A 318 target case study.” Wallach, I. et al. Nature Sci. Rep. 2024, 14, 7526. (DOI: 10.1038/s41598-024-54655-z)